产品详情 |
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Antigenic Specificity | GAD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB, IF, IP • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:10 - 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-GAD2 polyclonal antibody. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
Immunogen | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
Other Names | GAD65 |
Gene, Accession # | Gene ID: 2572, UniProt: Q05329 |
Catalog # | FNab03291 |
Price | |
Order / More Info | GAD2 Antibody from FINETEST |
Product Specific References | n/a |
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