产品详情 |
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Antigenic Specificity | PSTPIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB, IHC • WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PSTPIP1 polyclonal antibody. This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated wi |
Immunogen | proline-serine-threonine phosphatase interacting protein 1 |
Other Names | CD2BP1 |
Gene, Accession # | Gene ID: 9051, UniProt: O43586 |
Catalog # | FNab06903 |
Price | |
Order / More Info | PSTPIP1 Antibody from FINETEST |
Product Specific References | n/a |
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