| 产品详情 |
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| Antigenic Specificity | PTEN |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat, monkey |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, IHC, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-PTEN polyclonal antibody. This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produ |
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| Immunogen | phosphatase and tensin homolog |
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| Other Names | MMAC1, TEP1 |
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| Gene, Accession # | Gene ID: 5728, UniProt: P60484 |
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| Catalog # | FNab09821 |
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| Price | |
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| Order / More Info | PTEN Antibody from FINETEST |
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| Product Specific References | n/a |
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| 产品资料 |
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