| 产品详情 |
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| Antigenic Specificity | RASGRF1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IP • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-RASGRF1 polyclonal antibody. The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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| Immunogen | Ras protein-specific guanine nucleotide-releasing factor 1 |
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| Other Names | CDC25, GNRP, GRF1 |
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| Gene, Accession # | Gene ID: 5923, UniProt: Q13972 |
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| Catalog # | FNab07131 |
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| Price | |
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| Order / More Info | RASGRF1 Antibody from FINETEST |
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| Product Specific References | n/a |
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