| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | HUS1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | immunogen affinity purified |
|---|
| Size | 100µg |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA, IHC, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit anti-HUS1 polyclonal antibody. The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results i |
|---|
| Immunogen | HUS1 checkpoint homolog (S. pombe) |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Gene ID: 3364, UniProt: O60921 |
|---|
| Catalog # | FNab04082 |
|---|
| Price | |
|---|
| Order / More Info | HUS1 Antibody from FINETEST |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|