产品详情 |
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Antigenic Specificity | LITAF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB, IHC, IP • WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-LITAF polyclonal antibody. Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have b |
Immunogen | lipopolysaccharide-induced TNF factor |
Other Names | PIG7, SIMPLE |
Gene, Accession # | Gene ID: 9516, UniProt: Q99732 |
Catalog # | FNab04798 |
Price | |
Order / More Info | LITAF Antibody from FINETEST |
Product Specific References | n/a |
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