产品详情 |
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Antigenic Specificity | VDR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-VDR polyclonal antibody. This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation |
Immunogen | vitamin D (1,25- dihydroxyvitamin D3) receptor |
Other Names | NR1I1, VDR, Vitamin D3 receptor |
Gene, Accession # | Gene ID: 7421, UniProt: P11473 |
Catalog # | FNab09390 |
Price | |
Order / More Info | VDR Antibody from FINETEST |
Product Specific References | n/a |
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