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| Product Name | TRKC, Active, Recombinant, Human, GST-Tag |
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| Description | Purified (~50%). TRKC, a member of the insulin receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats. Source: Recombinant corresponding to aa456-825 from human TRKC, fused to GST-tag at N-terminal, expressed in Sf9 cells via a baculovirus expression system. Molecular Weight: ~68kD Applications: Suitable for use in the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TRKC, Active, Recombinant, Human, GST-Tag (NT-3 Growth Factor Receptor, GP145-TrkC, Trk-C, Neurotrophic Tyrosine Kinase Receptor Type 3, TrkC Tyrosine Kinase, NTRK3) |
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| Gene, Accession, CAS # | Accession: NM_002530, SwissProt: Q16288 |
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| Catalog # | 137386 |
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| Order / More Info | TRKC, Active, Recombinant, Human, GST-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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