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| Product Name | TrkC-Fc Chimera, Human |
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| Description | Purity ~95% (SDS-PAGE). TrkC is a member of the tropomyosin-related kinase receptor family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3). Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. TrkC is a heavily glycosylated molecule with 13 potential N-linked glycosylation sites within the extracellular domain. Source: TrkC-Fc Chimera, from human DNA sequence encoding the signal peptide and extracellular domain of human TrkC aa1-428 was fused to the Fc region of human IgG1 aa93-330. The chimeric protein was expressed in modified human 293 cells. Molecular Weight: ~85kD-150kD with post-translational modification and ~71.9kD unmodified. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TrkC-Fc Chimera, Human (Tropomyosin-Related Kinase Receptor, NT-3 Growth Factor Receptor, Neurotrophic Tyrosine Kinase Receptor Type 3, TrkC Tyrosine Kinase, GP145-TrkC, Trk-C, NTRK3, TRKC, TrkC-Fc Chimera) |
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| Gene, Accession, CAS # | SwissProt: Q16288 |
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| Catalog # | 215492 |
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| Order / More Info | TrkC-Fc Chimera, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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