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| Product Name | CK1 Delta, Recombinant, Human, GST-Tag (Casein Kinase I Isoform delta, CSNK1D, HCKID, CK1D) |
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| Description | Purified (~70-90%). CK1d is a member of the CK1 family of serine/threonine protein kinases which play an important role in diverse cell processes, including DNA replication and repair. CK1d is a regulator of Yes-associated protein (YAP) transcription coactivator which is a key regulator of organ size and a candidate human oncogene. CK1d is activated by CCK2R and this then phosphorylates PKD2 at Ser244. Phosphorylation of PKD2 leads to its nuclear accumulation and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells. CKId can phosphorylate in vitro deoxycytidine kinase (dCK) which is a key enzyme in the salvage of deoxynucleosides. Phosphorylation of dCK by CKId in vitro correlates with increased activity of this enzyme. Source: Recombinant protein corresponding to human CK1 Delta, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~72kD Specific Activity: 82nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001893 |
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| Catalog # | 499887 |
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| Order / More Info | CK1 Delta, Recombinant, Human, GST-Tag (Casein Kinase I Isoform delta, CSNK1D, HCKID, CK1D) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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