| 产品名称 |
CK1 Epsilon, Recombinant, Human, GST-Tag (Casein Kinase I epsilon, CSNK1E, HCKIE, MGC10398, CK1E) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | CK1 Epsilon, Recombinant, Human, GST-Tag (Casein Kinase I epsilon, CSNK1E, HCKIE, MGC10398, CK1E) |
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| Description | Purified (~70-90%). CK1e is a member of the CK1 family of serine/threonine protein kinases which play an important role in diverse cell processes, including DNA replication and repair. CK1e is a regulator of Yes-associated protein (YAP) transcription coactivator which is a key regulator of organ size and a candidate human oncogene. CK1e is activated by CCK2R and this then phosphorylates PKD2 at Ser244. Phosphorylation of PKD2 leads to its nuclear accumulation and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells. CKIe can phosphorylate topoisomerase (topo) IIalpha at serine-1106 and this regulates the enzyme activity and sensitivity to topo II-targeted drugs. Source: Recombinant protein corresponding to human CK1 Epsilon, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~72kD Specific Activity: 46nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001894 |
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| Catalog # | 499888 |
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| Price | |
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| Order / More Info | CK1 Epsilon, Recombinant, Human, GST-Tag (Casein Kinase I epsilon, CSNK1E, HCKIE, MGC10398, CK1E) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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