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| Antigenic Specificity | Nectin-2, Mouse |
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| Clone | 52-57 |
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| Host Species | Rat |
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| Reactive Species | mouse, human |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 µg |
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| Concentration | 100 µg/ml |
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| Applications | frozen sections, immunoassay, IF, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice. Monoclonal antibody 502-57 has been raised against the extracellular domain of mouse nectin-2. The antibody cross reacts with human nectin-2. |
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| Immunogen | n/a |
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| Other Names | Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Murine herpes virus entry protein B, mHveB, Nectin cell adhesion molecule 2, Poliovirus receptor homolog, Poliovirus receptor-related protein 2, CD112. |
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| Gene, Accession # | Nectin2, Mph, Pvr, Pvrl2, Pvs |
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| Catalog # | HM1052F |
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| Price | |
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| Order / More Info | Nectin-2, Mouse Antibody from HYCULT BIOTECH |
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| Product Specific References | n/a |
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