| 产品详情 |
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| Antigenic Specificity | Lamin A+C |
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| Clone | JOL2 |
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| Host Species | Mouse |
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| Reactive Species | human, African green monkey |
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| Isotype | IgG1 |
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| Format | supernatant |
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| Size | 1ml |
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| Concentration | n/a |
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| Applications | ICC/IF, IHC-Fr, IHC-P, WB, IP, Flow Cyt |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-Lamin A+C [JOL2]. This antibody reacts with both recombinant and native Lamin A and C in humans. Binds to an epitope between amino acids 464-572 |
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| Immunogen | Recombinant human lamin A |
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| Other Names | 70 kDa Lamin, Cardiomyopathy dilated 1A (autosomal dominant), CDCD1, CDDC; Charcot Marie Tooth Disease Axonal Type 2B1, CMD1A, CMT2B1, EMD2; FPL, FPLD, HGPS, IDC, Lamin A/C, Lamin A/C Isoform 1Precursor, Lamin A/C Isoform 2, Lamin A/C Isoform 3, LDP1, LFP; LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant), LMN 1, LMN A; LMN C, LMN1, LMNA, LMNC, NY REN 32 antigen, PRO1; Progeria 1 (Hutchinson Gilford Type), Renal carcinoma antigen NY REN 32, Renalcarcinoma antigen NYREN32 |
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| Gene, Accession # | n/a |
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| Catalog # | IQ332 |
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| Price | |
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| Order / More Info | Lamin A+C Antibody from IMMUQUEST LTD. |
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| Product Specific References | Gibbs-Seymour I1 et al. Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage.Aging Cell. 2015 Apr;14(2):162-9. doi: 10.1111/acel.12258. Epub 2015 Jan 23. IHC ; Human PUBMED Iglesias-Guimarais V et al. Apoptotic DNA Degradation into Oligonucleosomal Fragments, but Not Apoptotic Nuclear Morphology, Relies on a Cytosolic Pool of DFF40/CAD Endonuclease. J Biol Chem 287:7766-79 (2012). WB ; HumanPUBMED Harrigan JA et al. Replication stress induces 53BP1-containing OPT domains in G1 cells. J Cell Biol 193:97-108 (2011). ICC/IF ; HumanPUBMED Gudise S et al. Samp1 is functionally associated with the LINC complex and A-type lamina networks. J Cell Sci 124:2077-85 (2011)PUBMED Harten IA et al. Age-Dependent Loss of MMP-3 in Hutchinson-Gilford Progeria Syndrome. J Gerontol A Biol Sci Med Sci : (2011)PUBMED Toulany M et al. Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation. Breast Cancer Res 13:R28 (2011). WB ; HumanPUBMED Mamchaoui K et al. Immortalized pathological human myoblasts: towards a universal tool for the study of neuromuscular disorders. Skelet Muscle 1:34 (2011). ICC/IF ; HumanPUBMED Negroni E et al. In vivo myogenic potential of human CD133 muscle-derived stem cells: a quantitative study. Mol Ther 17:1771-8 (2009). ICC/IF ; HumanPUBMED |
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