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| Product Name | CTRP13, globular domain, Recombinant, Human |
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| Description | Purity >95% (SDS-PAGE). CTRP13 (C1qTNF-related protein 13) belongs to a highly conserved family of adiponectin paralogs. CTRP13 is an adipokine that promotes glucose uptake in adipocytes, myotubes and hepatocytes via activation of the AMPK signaling pathway. CTRP13 ameliorates lipid-induced insulin resistance in hepatocytes through suppression of the SAPK/JNK stress signaling that impairs the insulin signaling pathway. CTRP13 reduces glucose output in hepatocytes by inhibiting the mRNA expression of gluconeogenic enzymes, glucose-6-phosphatase and the cytosolic form of phosphoenolpyruvate carboxykinase. CTRP13 has insulin-sensitizing activity and is important in glucose homeostasis. CTRP13 is preferentially expressed by adipose tissue and the brain in mice and predominantly by adipose tissue in humans. Sequence: The globular domain of human CTRP13 (aa 120-255) is fused at the C-terminus to a His-tag. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CTRP13, globular domain, Recombinant, Human (His) (C1qTNF-related Protein 13, C1QTNF13, C1QL3, C1ql, K100, Complement C1q Tumor Necrosis Factor-related Protein 13) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44687 |
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| Order / More Info | CTRP13, globular domain, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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