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| Product Name | 14-3-3, beta, Recombinant, Human |
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| Description | Purity ≥ 90% by SDS-PAGE . The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma epsilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Source: Synthetic corresponding to aa1-246 of human 14-3-3 beta expressed in E.coli. AA Sequences: MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLIPN ATQPESKVFY LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN Applications: Sui |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 14-3-3, beta, Recombinant, Human (Tyrosine 3-monooxygenase/tryptopan 5-monooxygenase activation protein, beta polypeptide) |
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| Gene, Accession, CAS # | Accession: NP_003395 |
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| Catalog # | 0014-02D |
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| Order / More Info | 14-3-3, beta, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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