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| Product Name | 14-3-3, beta, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). 14-3-3, a family of acidic and soluble proteins, highly conserved in aa sequences from yeast to mammals, is expressed in all eukaryotic cells. Seven isoforms (beta, gamma, epsilon, eta, zeta, sigma and tau/theta) encoded by seven distinct genes are identified in mammals and forms homo- and hetero- dimeric cup-shaped structures. As 14-3-3 is interacted with more than 100 binding partners, it regulates key proteins involved in various biological processes such as signal transduction, cell cycle, transcriptional control, cell proliferation, apoptosis, and ion channel physiology. Most 14-3-3 requires phosphorylation of serine or threonine residues in the target sequence. This protein is abundantly expressed in the brain and has been detected in the cerebrospinal fluid of patients with different neurological disorders. Source: Recombinant corresponding to aa1-246, with additional 3aa-GSH at N-term, from human 14-3-3b, expressed in E.coli. Molecular Weight: ~30kD |
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| Size | 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 14-3-3, beta, Recombinant, Human (Protein 1054, Protein Kinase C Inhibitor Protein 1, KCIP-1, 14-3-3 Protein beta/alpha, N-terminally Processed, YWHAB) |
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| Gene, Accession, CAS # | SwissProt: P31946, P63104 |
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| Catalog # | 0014-02R |
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| Order / More Info | 14-3-3, beta, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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