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| Antigenic Specificity | Charged Multivesicular Body Protein 6 (CHMP6) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Sheep |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery oftransmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-II complex on endosomal membranes.Subunit: Component of the endosomal sorting required for transport complex III (ESCRT-III), at least composed of CHMP1A, CHMP1B, CHMP2A, CHMP2B, CHMP3/VPS24, CHMP4A/SHAX2, CHMP4B/SHAX1, CHMP4C/SHAX3, CHMP5/SNF7DC2 and CHMP6/VPS20. In the complex, it interacts directly with CHMP4A, CHMP4B and CHMP4C. Interacts directly with SNF8, VPS25 and VPS36 components of the ESCRT-II complex.Subcellular location: Intracytoplasmic membrane. Endosome membrane, Lipid-anchor . Note: Localizes to endosomal membranes. Also known as: Charged multivesicular body protein 6, Chromatin-modifying protein 6. |
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| Immunogen | A synthetic peptide from the c-terminal region of mouse CHMP6 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with rat's. |
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| Other Names | chmp6|vps20|2400004G01Rik|VPS20|RGD1565325|chmp6l|flj11749l|wu:fb79d02|zgc:110067 |
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| Gene, Accession # | Gene ID: 208092,287873 |
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| Catalog # | ABIN350232 |
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| Price | |
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| Order / More Info | Charged Multivesicular Body Protein 6 (CHMP6) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15782199 |
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