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Antigenic Specificity | Charged Multivesicular Body Protein 3 (CHMP3) (N-Term) |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Function: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery oftransmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. Required for sorting/trafficking of EGF receptor. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins.Subcellular location: Cytoplasm, cytosol. Membrane, Lipid-anchor.Tissue specificity: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Also known as: Chromatin-modifying protein 3, Vacuolar protein-sorting-associated protein 24, hVps24, Neuroendocrine differentiation factor, Charged multivesicular body protein 3, VPS24, NEDF. |
Immunogen | A synthetic peptide from the n-terminal of human CHMP3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse. |
Other Names | CG9779|Dmel\\CG9779|Vps24|dvps24|vps24|VPS24|CHMP3|GB15107|wu:fb47g01|zgc:76972|NEDF|25.1|4921505F14Rik|9130011K15Rik|CGI-49|D6Ertd286e |
Gene, Accession # | Gene ID: 51652,66700,282834 |
Catalog # | ABIN350227 |
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Order / More Info | Charged Multivesicular Body Protein 3 (CHMP3) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 18669648, 15815621, 14505569, 14505570, 11549700 |
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