产品详情 |
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Product Name | ABT 888 |
Description | Purity >99% by HPLC. Potent inhibitor of Poly(ADP-Ribose) polymerase PARP-1 and PARP-2. Its potency against PARP is validated to be 5 nM in vitro. Does not inhibit other NAD-binding enzymes. It significantly increased tumour growth delay resulting from radiation and DNA-damaging agents at well-tolerated doses in murine models. It shows minimal CYP450 inhibition and induction. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide, Veliparib |
Gene, Accession, CAS # | CAS: 912444-00-9 |
Catalog # | LS-H10737 |
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Order / More Info | ABT 888 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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