| 产品详情 |
| Edit |   |
|---|
| Product Name | Ezrin (Thr567), Radixin (Thr564), Moesin (Thr558), phosphorylated, Blocking Peptide |
|---|
| Description | The ezrin, radixin and moesin (ERM) proteins function as linkers between the plasma membrane and the actin cytoskeleton and are involved in cell adhesion, membrane ruffling and microvilli formation (1). ERM proteins undergo intra or intermolecular interaction between their amino- and carboxy-terminal domains, existing as inactive cytosolic monomers or dimers (2). Phosphorylation at a carboxy-terminal threonine residue (Thr567 of ezrin, Thr564 of radixin, Thr558 of moesin) disrupts their amino- and carboxy-terminal association and may play a key role in regulating ERM protein conformation and function (3,4). Phosphorylation at Thr567 of ezrin is required for cytoskeletal rearrangements and oncogene-induced transformation (5). Ezrin is also phosphorylated at tyrosine residues upon growth factor stimulation. Phosphorylation of Tyr353 of ezrin transmits a survival signal during epithelial differentiation (6). Description: This peptide is used to block Phospho-Ezrin (Thr567)/Radixin (Thr564 |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | IHC |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | E9100A |
|---|
| Price | |
|---|
| Order / More Info | Ezrin (Thr567), Radixin (Thr564), Moesin (Thr558), phosphorylated, Blocking Peptide from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|