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Product Name | Human IL1A / IL-1 Alpha Protein (Recombinant) |
Description | Purity >95% by SDS-PAGE, MW: 18 kDa. Interleukin 1 alpha (IL-1a) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1a signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic Toll/IL-1 receptor (TIR) domain adapter. IL-1a and the independently regulated IL-1β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | IL1A, Hematopoietin-1, IL-1 alpha, IL1, IL1-ALPHA, IL1 Alpha, Interleukin-1 alpha, IL-1A, IL1F1, Pro-interleukin-1-alpha, Preinterleukin 1 alpha, Interleukin 1, alpha |
Gene, Accession, CAS # | IL1A, Gene ID: 3552 |
Catalog # | LS-G23564 |
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Order / More Info | Human IL1A / IL-1 Alpha Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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