产品详情 |
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Product Name | LH 846 |
Description | Purity >98%. LH 846 is a benzothiazole analog that selectively inhibits casein kinase (CK) 1Delta (IC50 = 290 nM). It inhibits CK1e and CK1Alpha at much higher concentrations (IC50 s = 1.3 and 2.5 µM, respectively) but does not inhibit CK2. LH 846 has been shown to inhibit CK1Delta-dependent phosphorylation and degradation of PER1 protein and to lengthen the circadian period in U2OS cells. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-(5-chloro-6-methyl-2-benzothiazolyl)-benzeneacetamide |
Gene, Accession, CAS # | CAS: 639052-78-1 |
Catalog # | LS-H8466 |
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Order / More Info | LH 846 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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