产品详情 |
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Product Name | LLP-3 |
Description | Purity >95%. Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins. LLP-3 is a cell-permeable ligand of Survivin that blocks its interaction with Ran, resulting in the induction of apoptosis (IAP) in glioma stem cells (IC50 = 31 µM). It abolishes the growth of glioblastoma multiforme cell in spheres and in tumor slice cultures. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[3,5-bis (phenylmethoxy)phenyl]-6-(5-chloro-2-hydroxyphenyl)-1,2-dihydro-2-oxo-3-pyridinecarbonitrile |
Gene, Accession, CAS # | CAS: 1453835-43-2 |
Catalog # | LS-H8495 |
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Order / More Info | LLP-3 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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