| 产品详情 |
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| Product Name | LM22A-4 |
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| Description | Purity >98% by NMR, TLC. LM22A-4 is a small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, LM22A-4 caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats. Improves respiratory function in a mouse models of Rett syndrome. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N'N' Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide |
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| Gene, Accession, CAS # | CAS: 37988-18-4 |
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| Catalog # | LS-H14740 |
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| Order / More Info | LM22A-4 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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