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| Antigenic Specificity | Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1, alpha Polypeptide) (ITGAL) |
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| Clone | WT-1 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG2a |
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| Format | biotin conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of and subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes. ABIN133275is specific for the subunit of LFA-1. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1 (1). Applications include immunoprecipitation, flow cytometric analysis, immunohistochemistry, cryostat sections, and in vivo/in vitro functional studies (1,2,3). |
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| Immunogen | Rat Splenic PHA blasts . Fusion Partner: Mouse myeloma cell line PAI . Donor: BALB/c spleen |
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| Other Names | ITGAL |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN133275 |
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| Order / More Info | Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1, alpha Polypeptide) (ITGAL) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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