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| Product Name | FAS, Recombinant, Human, aa26-171, GST-Tag (Tumor Necrosis Factor Receptor Superfamily Member 6 Protein) |
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| Description | Purity ~90% (SDS-PAGE). Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). Source: Recombinant protein corresponding to aa26-171 from human FAS, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~43.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Apo-1 antigen, Apoptosis-mediating surface antigen, FAS FASLG receptor, CD95 |
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| Gene, Accession, CAS # | SwissProt: P25445 |
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| Catalog # | 373277 |
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| Order / More Info | FAS, Recombinant, Human, aa26-171, GST-Tag (Tumor Necrosis Factor Receptor Superfamily Member 6 Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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