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| Product Name | Nicotinamide N-Methyltransferase, Recombinant, Human, His-Tag (NNMT) |
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| Description | Purity ~98% (SDS-PAGE). N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. NNMT is an important cytosolic methyltransferase catalyzing the N-methylation of nicotinamide, pyridines and structural analogs, playing a crucial role in the biotransformation and detoxification of many xenobiotic compounds. In the N-methylation process, NNMT uses S-adenosyl methionine as the methyl donor and nicotinamide as methyl acceptor. NNMT is mostly expressed in the liver, and a lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. It may also play an important role in regulating biological processes related to N-methyl nicotinamide such as anti-inflammatory, anti-thrombotic, vasoprotective, and gastroprotective properties. Increased NNMT activity was reported in many kinds of tumors. NNMT is a potential biomarker and therapeutic target in caner diagnosis and treatment. NNMT serum levels have significance in the premature de |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NNMT |
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| Gene, Accession, CAS # | NNMT, Gene ID: 4837 |
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| Catalog # | 220104 |
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| Order / More Info | Nicotinamide N-Methyltransferase, Recombinant, Human, His-Tag (NNMT) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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