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| Product Name | Smad4, Recombinant, Human |
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| Description | Purity ≥ 90% (SDS-PAGE). SMAD4 belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription and may also act as a tumor suppressor. Recombinant protein corresponding to aa1-552 of human SMAD4 with a N-terminal His tag expressed in E. coli Purified by using conventional chromatography techniques. Source: Human SMAD4 protein, His-tagged was expressed in E. coli. AA Sequences: MGSSHHHHHH SSGLVPRGSH MDNMSITNTP TSNDACLSIV HSLMCHRQGG ESETFAKRAI ESLVKKLKEK KDELDSLITA ITTNGAHPSK CVTIQRTLDG RLQVAGRKGF PHVIYARLWR WPDLHKNELK HVKYCQYAFD LKCDSVCVNP YHYERVVSPG IDLSGLTLQS NAPSSMMVKD EYVHDFEGQP SLSTEGHSIQ TIQHPPSNRA STETYSTPAL LAPSESNATS TANFPNIPVA STSQPASILG GSHSEGLLQI ASGPQPGQQQ NGFTGQPATY HHNSTTTWTG SRT |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Smad4, Recombinant, Human (DPC4, Small Mothers Against Decapentaplegic Deleted in Pancreatic Carcinoma) |
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| Gene, Accession, CAS # | Accession: NP_005350 |
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| Catalog # | S1014-54F1 |
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| Order / More Info | Smad4, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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