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| Product Name | Smad3, Recombinant, Human, aa1-425, His-Tag |
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| Description | Purity ~90% (SDS-PAGE) Purified by immunoaffinity chromatography. SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases. Recombinant SMAD3 protein was expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant corresponding aa1-425 from human SMAD3, his-tagged, expressed in E. coli (NP_005893). AA sequence: MGSSHHHHHH SSGLVPRGSH MSSILPFTPP IVKRLLGWKK GEQNGQEEKW CEKAVKSLVK KLKKTGQLDE LEKAITTQNV NTKCITIPRSLDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELRAMELCE FAFNMKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEIPAEF PPLDDYSHSI PENTNFPAGI EPQSNIPETP PPGYLSEDGE TSDHQMNHSM DAGSPNLSPN PMSPAHNNLD LQPVTYCEPA FWCSISYYEL NQRVGETFHASQPSMTVDGF TDPSN |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Smad3, Recombinant, Human, aa1-425, His-Tag (Small Mothers Against Decapentaplegic Deleted in Pancreatic Carcinoma) |
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| Gene, Accession, CAS # | Accession: NP_005893 |
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| Catalog # | S1014-53T |
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| Order / More Info | Smad3, Recombinant, Human, aa1-425, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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