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| Product Name | MIC1, Recombinant, Human |
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| Description | Purity ~98% (SDS-PAGE and HPLC). GDF-15 belongs to the TGF-β cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in placenta and to a much lesser extent in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest a role for GDF-15 in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 114aa polypeptide chains. Source: Recombinant protein corresponding to human GDF-15/MIC |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MIC1, Recombinant, Human (Uncharacterized Protein C18orf8, Colon Cancer-associated Protein Mic1, Mic-1, C18orf8, FLJ23453) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149613 |
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| Price | |
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| Order / More Info | MIC1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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