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| Product Name | NT-4, Recombinant, Human (Neurotrophin 4) |
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| Description | Purity > 98% by SDS-PAGE and HPLC analyses. Neurotrophin-4 (NT-4/NT-5) is a potent neurotrophic factor which supports the growth and survivability of nerve and/or glial cells. NT-4 is a neurotrophic factor structurally related to beta-NGF, BDNF and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. The active form of human NT-4 is a dimer, formed by two identical 130 amino acid subunits, which is held together by strong hydrophobic interactions. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0kD polypeptide monomers (260 total amino acid residues). Endotoxin: < 0.1ng/ug (1EU/ug) Responding Cells (partial list): Nerve, glial cells Biological Activity: The ED50 was determined by the dose-dependent induction of ch |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N6000-11 |
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| Order / More Info | NT-4, Recombinant, Human (Neurotrophin 4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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