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| Product Name | NT-3, Recombinant, Human (Neurotrophin-3, Neurotrophic factor, Nerve growth factor-2, NGF-2, HGNF) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. NT-3 is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-4.These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures.NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors.NT-3 promotes the growth and survival of nerve and glial cells.The amino acid sequences of human, murine and rat NT-3 are identical.Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6kD polypeptide monomers (240 total amino acid residues).Human and Mouse NT-3 sequences are identical. Biological Activity: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50ng/ml. AA Sequence: MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT Crossr |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143454 |
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| Order / More Info | NT-3, Recombinant, Human (Neurotrophin-3, Neurotrophic factor, Nerve growth factor-2, NGF-2, HGNF) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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