| 产品详情 |
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| Product Name | Human HLA-DRB1 Protein (Recombinant His tag) |
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| Description | Purity >85% by SDS-PAGE. HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Recombinant human HLA-DRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, Human leucocyte antigen DRB1, MHC class II antigen DRB1*10, MHC class II antigen, MHC class II antigen DRB1*1, HLA-DRB2, Lymphocyte antigen DRB1, SS1 |
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| Gene, Accession, CAS # | HLA-DRB1, Gene ID: 3123 |
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| Catalog # | LS-G2798 |
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| Order / More Info | Human HLA-DRB1 Protein (Recombinant His tag) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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