| 产品详情 |
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| Product Name | CXCR3 Antagonist |
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| Description | Purity ~90% (HPLC). An arylsulfonamide derivative that acts as a CXCR3 antagonist (IC50 = 192nM against CXCL10-induced chemotaxis of hCXCR3-overexpressing L1.2 cells) with good aqueous solubility (>100uM at pH 7.4). Shown to be orally available in mice (83% bioavailability; t1/2 = 1h; 10mg/kg p.o.) in vivo and display a medium intrinsic clearance (CIint = 17uL/min/mg) in in vitro mouse liver microsome stability test. Solubility: DMSO Primary Target: CXCR3 Primary Target IC50: 192nM Molar Mass: 466.46 |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CXCR3 Antagonist (GPR9 Antagonist, 4-cyano-N-(3-fluoro-4-(1H-tetrazol-5-yl)benzyl)-N-(2-fluorobenzyl)benzenesulfonamide, AS612568, EMD1205395, CD183 Antagonist) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217298 |
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| Price | |
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| Order / More Info | CXCR3 Antagonist from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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