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| Product Name | PHAP I, CT, Control Peptide (Putative HLA DR-associated Protein) |
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| Description | Synthetic peptide corresponding to amino acids at C-terminus of human PHAP I (1). Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after being released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activates procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3,-6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs ) were recently identified as important regulators of mitochondrion apoptosis (1). PHAP appears to facilitate apoptosome-mediated caspase-9 activation and to stimulates the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras and Myc-mediated cell transformation. Applications: Suitable for use in ELISA and Antibody Blocking. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P3368-02A |
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| Order / More Info | PHAP I, CT, Control Peptide (Putative HLA DR-associated Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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