| 产品详情 |
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| Product Name | PHAP, NT, Control Peptide |
| Description | Synthetic peptide corresponding to amino acids at amino terminus of human PHAP (1). Corresponding antibody detects all three identified isoforms of PHAP: PHAP I, PHAP I2a and PHAP III. Species Crossreactivity: Species Crossreactivity: human, mouse and rat. Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3,-6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins ( PHAPs ) were recently identified as important regulators of mitochondrion apoptosis (1). PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also |
| Size | 50ug |
| Concentration | n/a |
| Applications | ELISA WB |
| Other Names | PHAP, NT, Control Peptide (Putative HLA DR-associated Protein, Putative Human HLA Class II Associated Protein, Acidic (Leucine-rich) Nuclear Phosphoprotein 32 Family Member B, ANP32B, Acidic Leucine-rich Nuclear Phosphoprotein 32 Family Member A, ANP32A, Acidic Nuclear Phosphoprotein pp32, I1PP2A, LANP, MAPM, PHAP1, PHAPI2, PHAPIII, PP32) |
| Gene, Accession, CAS # | n/a |
| Catalog # | P3368-01A |
| Price | |
| Order / More Info | PHAP, NT, Control Peptide from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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