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Product Name | α-Tocotrienol |
Description | The four tocopherols (α, β, .delta., and γ) and four tocotrienols (α, β, .delta., and γ) are forms of vitamin E, which is known for its antioxidant activity.{3679} Tocotrienols are found at high concentrations in palm oil and rice bran. Recent studies show tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.{14290} Compared to other tocotrienols, α-tocotrienol exhibits the most potent neuroprotective actions in rat striatal neurons. At concentrations of 0.1-10 µM, α-tocotrienol significantly suppresses H2O2-induced cell death and provides protection against S-nitrocysteine-induced cell death and SIN-1 toxicity in a concentration dependent manner.{14290} HT4 cells, that are microinjected with 10−19 mol of α-tocotrienol into the cytosolic, are protected against glutamate-induced cell death by suppressing early activation of c-Src kinase and 12-LO.{14292} |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | vitamin E tocopherols tocotrienols antioxidants apoptosis palm oils rice brans neuroprotectors neuroprotection H2O2 hydrogen peroxides cells death S-nitrocysteines SIN-1 toxicity HT4 cytosolic glutamatec-Src kinases 12-lipoxygenases 12-LOs |
Gene, Accession, CAS # | CAS: 58864-81-6 |
Catalog # | 10008377-1 |
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Order / More Info | α-Tocotrienol from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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