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| Product Name | MEK1 Inhibitor (PD98059, 2'-amino-3'- methoxyflavone) |
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| Description | Purity ~95% (HPLC). PD98059 is a potent and selective cell permeable inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK, thereby inhibiting the phosphorylation and the activation of MAP kinase. In pheochromocytoma (PC12) cells, it completely blocks the increase in MAP kinase activity produced by NGF. PD98059 is an invaluable tool to help elucidate the role of the MAPK cascade in a variety of biological systems. Molecular Weight: ~267.3 Biological Activity: IC50=2uM Solubility: DMSO (~6.5mg/ml), anhydrous DMSO (~25mg/ml), ethanol (~0.6mg/ml). It is recommended that this compound be diluted directly from the DMSO stock into buffered media with stirring. Please note that bovine serum albumin at a concentration of 6.6mg/ml has been observed to prevent the precipitation of PD98059 in aqueous media. |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M2865-17B |
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| Order / More Info | MEK1 Inhibitor (PD98059, 2'-amino-3'- methoxyflavone) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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