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| Product Name | MEK1, 2 Inhibitor (U0126) |
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| Description | Purity ≥99% (HPLC, TLC). Selective inhibitor of the mitogen-activated protein kinase kinases, MEK-1 and MEK-2, with 100-fold higher potency than PD 98059, but is, at most, a weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4. U0126 is an inhibitor of AP-1 transactivation in cell-based reporter assays. In aqueous and certain organic solvents M2865-50A exists as an equilibrium mixture of 2 isomers which cannot be permanently separated. The 2 individual isomers have equivalent biological activity because they give rise to the same equilibrium mixture of isomes in aqueous solutions. Synonyms: MEK1, 2 Inhibitor,; Bis[amino[(2-aminophenyl)thio]methylene]Butanedinitrile); 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene CAS No: 109511-58-2 |
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| Size | 25mg, 50mg, 100mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MEK1, 2 Inhibitor,; Bis[amino[(2-aminophenyl)thio]methylene]Butanedinitrile); 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M2865-50A |
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| Order / More Info | MEK1, 2 Inhibitor (U0126) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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