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| Product Name | Human IL-17RA (CD217) Fc tagged Recombinant |
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| Description | MW: 96,122 Da. Purity >98%, as determined by SDS-PAGE and HPLC. IL-17 is a potent regulator of the neutrophil response. Both IL-17A and IL-17F are capable of signaling through IL-17RA to induce granulopoietic factors such as G-CSF and stem cell factor which leads to expansion of neutrophil progenitors in the bone marrow and spleen, as well as expansion of mature neutrophils in peripheral blood. IL-17RA signaling up- regulates production of neutrophilic chemokines such as CXCL1 (KC), CXCL2, CXCL5 |
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| Size | 0.05 mg, 0.2 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Human IL-17 receptor Fc tag Recombinant; il-17ra; il17RA; interleukin-17 r] |
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| Gene, Accession, CAS # | IL17RA, Gene ID: 23765, Accession: NP_055154.3 |
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| Catalog # | MBS553248 |
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| Order / More Info | Human IL-17RA (CD217) Fc tagged Recombinant from MYBIOSOURCE INC. |
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| Product Specific References | • cloning and characterisation of rainbow trout interleukin (il) -17a/f2 and IL-17RA: expression during infection and bioactivity of the recombinant il-17a/f2. .Infect. Immun., Nov 2012; 10.1128/IAI.00599-12. • the il-17a/IL-17RA axis plays a proatherogenic role via the regulation of aortic myeloid cell recruitment .Circ. Res., Mar 2012; 110: 675 - 687. • a cc' loop decoy peptide blocks the interaction between act1 and IL-17RA to attenuate il-17- and il-25-induced inflammation .Sc |
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