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| Product Name | Recombinant Human Titin |
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| Description | 5398-5604aa; Partial of Isoform 6. MW: 27.2kD. Purity >90% as determined by SDS-PAGE. Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, ses to play a role in chromosome condens |
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| Size | 0.05 mg, 0.2 mg, 0.5 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Connectin; Rhabdomyosarcoma antigen MU-RMS-40.14] |
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| Gene, Accession, CAS # | TTN, Gene ID: 7273, Accession: NP_001243779.1 |
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| Catalog # | MBS1265279 |
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| Order / More Info | Recombinant Human Titin from MYBIOSOURCE INC. |
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| Product Specific References | Titins, giant proteins in charge of muscle ultrastructure and elasticity.Labeit S., Kolmerer B.Science 270:293-296(1995) Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity.Freiburg A., Trombitas K., Hell W., Cazorla O., Fougerousse F., Centner T., Kolmerer B., Witt C., Beckmann J.S., Gregorio C.C., Granzier H., Labeit S.Circ. Res. 86:1114-1121(2000) The complete gene sequence of titin, expression of an unusual ~700 kDa |
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