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| Product Name | Macrophage Migration Inhibitory Factor, active (MIF), Recombinant, Human |
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| Description | Purity ≥95% as determined by SDS-PAGE and HPLC. Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (ECO:0000269|PubMed:15908412, ECO:0000269|PubMed:17443469, ECO:0000269|PubMed:23776208). Biological Activity: Fully biologically active when compared to standard. The specific activity is determined by binding rhCD74 in a functional ELISA. |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase |
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| Gene, Accession, CAS # | MIF_HUMAN, SwissProt: P14174 |
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| Catalog # | 348169 |
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| Price | |
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| Order / More Info | Macrophage Migration Inhibitory Factor, active (MIF), Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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