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| Product Name | Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay™ ELISA Kit |
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| Description | Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay™ ELISA Kit is used for the quantitative determination of human total Tau protein. Tau is a microtubule associated protein found predominantly in neuronal axons of vertebrate brain. Tau protein is highly soluble and normally attached to axonal microtubules. Tau stabilizes the microtubules and makes them rigid. Tau interacts with actin in the cytoskeleton and neuronal outgrowth, anchors enzymes such as protein kinases and phosphatases, and regulates intracellular vesicle transport. Tau phosphorylation regulates both normal and pathological functions of this protein. Tau, in its hyperphosphorylated form, is the major component of paired helical filaments (PHFs), the building block of neurofibrillary lesions in Alzheimer's disease (AD). Hyperphosphorylation impairs the microtubule binding function of tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to neuronal degenerat |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T1034-25 |
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| Order / More Info | Tau, Total, Human (Tau Protein, Microtubule-associated Protein, MAP) BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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