| 产品名称 |
BRM, Bromodomain, Recombinant, Human, aa1367-1511, GST-tag (SMARCA2A/B, SWI/SNF ATPase, SMARCA2) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | BRM, Bromodomain, Recombinant, Human, aa1367-1511, GST-tag (SMARCA2A/B, SWI/SNF ATPase, SMARCA2) |
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| Description | Purity ~95% (SDS-PAGE). The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. BRM is a member of the SWI/SNF protein family, which forms part of a large ATP-dependent chromatin remodeling complex. This complex is required for transcriptional activation of genes normally repressed by chromatin. Source: Recombinant protein corresponding to aa1367-1511 from human BRM, fused to GST-tag at N-terminal, expressed in E. coli. Molecular Weight: ~43.7kD |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SMARCA2A/B; SWI/SNF ATPase |
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| Gene, Accession, CAS # | SMARCA2, Gene ID: 6595, SwissProt: P51531 |
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| Catalog # | 219502 |
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| Order / More Info | BRM, Bromodomain, Recombinant, Human, aa1367-1511, GST-tag (SMARCA2A/B, SWI/SNF ATPase, SMARCA2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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