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| Product Name | MLF1, Recombinant, Human, aa1-268. GST-Tag (Myeloid Leukemia Factor 1) |
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| Description | Purity ~90% (SDS-PAGE). Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. Source: Recombinant protein corresponding to aa1-268 from human MLF1, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~57.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Myelodysplasia-myeloid leukemia factor 1 |
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| Gene, Accession, CAS # | SwissProt: P58340 |
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| Catalog # | 374225 |
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| Order / More Info | MLF1, Recombinant, Human, aa1-268. GST-Tag (Myeloid Leukemia Factor 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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