| 产品详情 |
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| Product Name | Phomopsin A |
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| Description | Purity ≥98% (HPLC). Phomopsin A is an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids linked in an ansa macrocycle with a three amino acid tail, terminating in a dicarboxylic acid. Phomopsin A is a potent mycotoxin produced by the fungus Phomopsis leptostromiformis and is the causative agent of lupinosis in livestock fed infected lupins. Phomopsin A is an important bioprobe for understanding cellular structural proteins. It acts by selectively binding to dimeric tubulin, inhibiting the formation of the microtubule spindle to block cell division. Phomopsin A binds to tubulin at a site overlapping that of vinblastine and maytansine. Uniquely, phomopsin A protects tubulin from decay. Source: Phomposis leptostromiformis MST-FP2068 Solubility: Soluble in ethanol, methanol, DMF or DMSO. Slightly soluble in water. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-Oxa-5,8-diazabicyclo[10.3.1]hexadecane, cyclic peptide deriv.; 3-Chloro-erythro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(E)-2,3-didehydroisoleucyl-(E)-2,3-didehydroaspartic acid cyclic (15→3)-ether; NSC 381839 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P3970 |
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| Price | |
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| Order / More Info | Phomopsin A from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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