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| Product Name | Zoniporide dihydrochloride |
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| Description | Sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor that displays selectivity over other NHE isoforms (Ki values are 14, 2200 and 220000 nM for human NHE1, human NHE2 and rat NHE3 respectively). Inhibits NHE1 dependent 22Na+ uptake in vitro (IC50 = 14 nM) and provides cardioprotection from myocardial ischemic injury in vivo (EC50 = 0.25 nM). Also inhibits MMP2/9 activity and invasion in breast cancer cells. Purity 99%. MW (observed): 393.27 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine dihydrochloride. CP 597396 |
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| Gene, Accession, CAS # | CAS: 241799-10-0 |
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| Catalog # | 2727/10 |
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| Price | |
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| Order / More Info | Zoniporide dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21887327, 24466344 |
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| 产品资料 |
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