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| Product Name | ZK 200775 |
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| Description | Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo. Purity 99%. MW (observed): 409.25 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [[3,4-Dihydro-7-(4-morpholinyl)-2,3-dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]methyl]phosphonic acid. MPQX |
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| Gene, Accession, CAS # | CAS: 161605-73-8 |
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| Catalog # | 2345/10 |
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| Price | |
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| Order / More Info | ZK 200775 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 15797869 |
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| 产品资料 |
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