产品详情 |
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Product Name | ACHP |
Description | IκB kinase inhibitor (IC50 values are 8.5 and 250 nM for IKKβ and IKKα respectively). Selective for IKKα and IKKβ over IKK3, Syk and MAPKKK4 (IC50 values are > 20 μM). Inhibits DNA binding activity of NF-κB. Blocks NF-κB pathway in multiple myeloma cell lines; induces cell growth arrest and apoptosis. Purity 97%. MW (observed): 364.44 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile |
Gene, Accession, CAS # | CAS: 406208-42-2 |
Catalog # | 4547/10 |
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Order / More Info | ACHP from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25714914, 26337045, 27004406, 27926864 |
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