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CTSL, Recombinant, Human, aa18-333, His-Tag (Cathepsin L1, Cathepsin L1 Isoform 1, CATL, CTSL1, MEP) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | CTSL, Recombinant, Human, aa18-333, His-Tag (Cathepsin L1, Cathepsin L1 Isoform 1, CATL, CTSL1, MEP) |
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| Description | Purity ~85% (SDS-PAGE). CTSL, also known as cathepsin L1 isoform 1, is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. Source: Recombinant protein corresponding to aa18-333 from human CTSL, fused to His-Tag, expressed in E. coli. Molecular Weight: ~38.3kD (339aa), confirmed by MALDI-TOF AA |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001244901, SwissProt: P07711 |
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| Catalog # | 377780 |
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| Order / More Info | CTSL, Recombinant, Human, aa18-333, His-Tag (Cathepsin L1, Cathepsin L1 Isoform 1, CATL, CTSL1, MEP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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